High concentrations of tissue inhibitor of matrix
metalloproteinase-1 and procollagen type III aminoterminal peptide were found
to significantly increase the risk of mortality, with the latter also
associated with incident CVD.
The study consisted of 922 participants from the
Framingham Study (mean age, 58 years). Researchers related incident CVD and
death to circulating concentrations of matrix metalloproteinase-9, log of
tissue inhibitor of matrix metalloproteinase-1, and log of procollagen type III
aminoterminal peptide (PIIINP).
During follow-u...