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Gene dosage of 9p21 linked with coronary atheromatous burden severity

Gene dosage of the risk variant 9p21 predicted coronary artery disease burden in a new study appearing in the Journal of the American College of Cardiology.

The Ottawa researchers performed this cross-sectional study on nondiabetic patients with CAD defined by coronary angiography having at least one epicardial stenosis >50%. They enrolled 950 patients with early onset ...
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December 8, 2010
EUROECHO 2010
COPENHAGEN, Denmark
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October 16, 2010
Acute Cardiac Care 2010
Copenhagen, Denmark
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October 13, 2010
World Stroke Congress (CME)
Seoul, Korea - Republic of
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"Dedicated and empowered patients are likely to be more adherent to treatment for chronic diseases, including hypertension...."


Relationship found between CYP2C19 and increased platelet reactivity in patients receiving clopidogrel

Carriage of cytochrome 2C19 variant was directly related to increased platelet reactivity and predicted the risk for high post-treatment platelet reactivity in patients who were treated with percutaneous coronary intervention and received high maintenance-dose clopidogrel, study findings suggested.

Korean researchers obtained this finding by examining patients (n=126) who had received high maintenance-dose clopidogrel (Plavix, Sanofi-Aventis) after PCI from previously registered Gyeongsang National University Hospital data. Researchers determined plate...

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